Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB/W F1 mice

Epoxy-fatty-acids (EpFAs), cytochrome P450 dependent arachidonic acid derivatives, have been suggested to have anti-inflammatory properties, though their effects on autoimmune diseases like systemic lupus erythematosus (SLE) have yet to be investigated. We assessed the influence of EpFAs and their m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Klocke, Jan, Ulu, Arzu, Wu, Kaiyin, Rudolph, Birgit, Dragun, Duska, Gollasch, Maik, Schunck, Wolf-Hagen, Hammock, Bruce D., Riemekasten, Gabriela, Enghard, Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586931/
https://ncbi.nlm.nih.gov/pubmed/31222024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45299-5
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