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A metabolomic perspective of griseofulvin-induced liver injury in mice

Griseofulvin (GSF) causes hepatic porphyria in mice, which mimics the liver injury associated with erythropoietic protoporphyria (EPP) in humans. The current study investigated the biochemical basis of GSF-induced liver injury in mice using a metabolimic approach. GSF treatment in mice resulted in s...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Liu, Ke, Yan, Jiong, Sachar, Madhav, Zhang, Xinju, Guan, Ming, Xie, Wen, Ma, Xiaochao
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699580/
https://ncbi.nlm.nih.gov/pubmed/26343413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.09.002
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