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Prostaglandin E(2) stimulates normal bronchial epithelial cell growth through induction of c-Jun and PDK1, a kinase implicated in oncogenesis
BACKGROUND: Cyclooxygenase-2-derived prostaglandin E(2) (PGE(2)), a bioactive eicosanoid, has been implicated in many biological processes including reproduction, inflammation and tumor growth. We previously showed that PGE(2) stimulated lung cancer cell growth and progression through PGE(2) recepto...
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Publié dans: | Respir Res |
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Auteurs principaux: | , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
BioMed Central
2015
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4699375/ https://ncbi.nlm.nih.gov/pubmed/26684827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0309-0 |
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