Induction of cathelicidin in normal and CF bronchial epithelial cells by 1,25-dihydroxyvitamin D(3)

BACKGROUND: Antimicrobial peptides (AMPs) such as cathelicidins contribute to initial defense of the airway against inhaled pathogens. Recent studies have shown that the hormonally active form of vitamin D(3), 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) up-regulates AMP gene expression in several e...

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Hauptverfasser: Yim, Sunghan, Dhawan, Puneet, Ragunath, Chandran, Christakos, Sylvia, Diamond, Gill
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099696/
https://ncbi.nlm.nih.gov/pubmed/17467345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2007.03.003
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