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PU.1 and Epigenetic Signals Modulate 1,25-Dihydroxyvitamin D(3) and C/EBPα Regulation of the Human Cathelicidin Antimicrobial Peptide Gene in Lung Epithelial Cells
LL-37, the only known human cathelicidin which is encoded by the human antimicrobial peptide (CAMP) gene, plays a critical role in protection against bacterial infection. We previously demonstrated that cathelicidin is induced by 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) in human airway epithelia...
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| Publié dans: | J Cell Physiol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6814306/ https://ncbi.nlm.nih.gov/pubmed/30387140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.27702 |
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