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Nicotine induces self-renewal of pancreatic cancer stem cells via neurotransmitter-driven activation of sonic hedgehog signaling

A small subpopulation of pancreatic cancer cells with characteristics of stem cells drive tumor initiation, progression and metastasis. A better understanding of the regulation of cancer stem cells may lead to more effective cancer prevention and therapy. We have shown that the proliferation and mig...

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Cancer
Hauptverfasser: Al-Wadei, Mohammed H., Banerjee, Jheelam, Al-Wadei, Hussein A.N., Schuller, Hildegard M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698183/
https://ncbi.nlm.nih.gov/pubmed/26689865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2015.10.003
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