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Nicotine stimulates pancreatic cancer xenografts by systemic increase in stress neurotransmitters and suppression of the inhibitory neurotransmitter γ-aminobutyric acid

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer mortality in Western countries. We have shown previously that four representative human PDAC cell lines were regulated by beta-adrenoreceptors via cyclic adenosine 3′,5′-monophosphate (cAMP)-dependent signaling. In the current stud...

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Autors principals: Al-Wadei, Hussein A. N., Plummer, Howard K., Schuller, Hildegard M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722153/
https://ncbi.nlm.nih.gov/pubmed/19131543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp010
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