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Differential modulation of nicotine-induced gemcitabine resistance by GABA receptor agonists in pancreatic cancer cell xenografts and in vitro

BACKGROUND: Pancreatic cancer is frequently resistant to cancer therapeutics. Smoking and alcoholism are risk factors and pancreatic cancer patients often undergo nicotine replacement therapy (NRT) and treatment for alcohol dependence. Based on our report that low dose nicotine within the range of N...

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Bibliografiske detaljer
Main Authors: Banerjee, Jheelam, Al-Wadei, Hussein AN, Al-Wadei, Mohammed H, Dagnon, Koami, Schuller, Hildegard M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190427/
https://ncbi.nlm.nih.gov/pubmed/25260978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-725
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