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Acyl-2-aminobenzimidazoles: a novel class of neuroprotective agents targeting mGluR5
Positive allosteric modulators (PAMs) of the metabotropic glutamate receptor 5 (mGluR5) are promising therapeutic agents for treating traumatic brain injury (TBI). Using computational and medicinal methods, the structure-activity relationship of a class of acyl-2-aminobenzimidazoles (1-26) is report...
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| Publicado en: | Bioorg Med Chem |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4697443/ https://ncbi.nlm.nih.gov/pubmed/25801156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.02.054 |
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