Dynamin-related Protein 1 Oligomerization in Solution Impairs Functional Interactions with Membrane-anchored Mitochondrial Fission Factor

Mitochondrial fission is a crucial cellular process mediated by the mechanoenzymatic GTPase, dynamin-related protein 1 (Drp1). During mitochondrial division, Drp1 is recruited from the cytosol to the outer mitochondrial membrane by one, or several, integral membrane proteins. One such Drp1 partner p...

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Foilsithe in:J Biol Chem
Main Authors: Clinton, Ryan W., Francy, Christopher A., Ramachandran, Rajesh, Qi, Xin, Mears, Jason A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2016
Ábhair:
Cell Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697186/
https://ncbi.nlm.nih.gov/pubmed/26578514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.680025
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