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Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity

Multiple isoforms of the mitochondrial fission GTPase dynamin-related protein 1 (Drp1) arise from the alternative splicing of its single gene-encoded pre-mRNA transcript. Among these, the longer Drp1 isoforms, expressed selectively in neurons, bear unique polypeptide sequences within their GTPase an...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Macdonald, Patrick J., Francy, Christopher A., Stepanyants, Natalia, Lehman, Lance, Baglio, Anthony, Mears, Jason A., Qi, Xin, Ramachandran, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697187/
https://ncbi.nlm.nih.gov/pubmed/26578513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.680181
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