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Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission

Cardiolipin (CL) is an atypical, dimeric phospholipid essential for mitochondrial dynamics in eukaryotic cells. Dynamin-related protein 1 (Drp1), a cytosolic member of the dynamin superfamily of large GTPases, interacts with CL and functions to sustain the balance of mitochondrial division and fusio...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Stepanyants, Natalia, Macdonald, Patrick J., Francy, Christopher A., Mears, Jason A., Qi, Xin, Ramachandran, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4551322/
https://ncbi.nlm.nih.gov/pubmed/26157169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-06-0330
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