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GFP fluorescence tagging alters dynamin-related protein 1 oligomerization dynamics and creates disassembly-refractory puncta to mediate mitochondrial fission

Green fluorescent protein (GFP)-tagging is the prevalent strategy to monitor protein dynamics in living cells. However, the consequences of appending the bulky GFP moiety to the protein of interest are rarely investigated. Here, using a powerful combination of quantitative fluorescence spectroscopic...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Montecinos-Franjola, Felipe, Bauer, Brianna L., Mears, Jason A., Ramachandran, Rajesh
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479153/
https://ncbi.nlm.nih.gov/pubmed/32901052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71655-x
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