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Alternate pleckstrin homology domain orientations regulate dynamin-catalyzed membrane fission

The self-assembling GTPase dynamin catalyzes endocytic vesicle scission via membrane insertion of its pleckstrin homology (PH) domain. However, the molecular mechanisms underlying PH domain–dependent membrane fission remain obscure. Membrane-curvature–sensing and membrane-curvature–generating proper...

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Detalhes bibliográficos
Main Authors: Mehrotra, Niharika, Nichols, Justin, Ramachandran, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952856/
https://ncbi.nlm.nih.gov/pubmed/24478459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-09-0548
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