A possible effector role for the pleckstrin homology (PH) domain of dynamin

The large GTPase dynamin plays a key role in clathrin-mediated endocytosis in animal cells, although its mechanism of action remains unclear. Dynamins 1, 2, and 3 contain a pleckstrin homology (PH) domain that binds phosphoinositides with a very low affinity (K(D) > 1 mM), and this interaction ap...

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Detaylı Bibliyografya
Asıl Yazarlar: Bethoney, Kelley A., King, Megan C., Hinshaw, Jenny E., Ostap, E. Michael, Lemmon, Mark A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720410/
https://ncbi.nlm.nih.gov/pubmed/19666604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906945106
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