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Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion.
Using the yeast two-hybrid system, we have identified a novel 62 kDa coiled-coil protein that specifically interacts with the GTP-bound form of Rab5, a small GTPase that regulates membrane traffic in the early endocytic pathway. This protein shares 42% sequence identity with Rabaptin-5, a previously...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1998
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170539/ https://ncbi.nlm.nih.gov/pubmed/9524116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.7.1930 |
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