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Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion.

Using the yeast two-hybrid system, we have identified a novel 62 kDa coiled-coil protein that specifically interacts with the GTP-bound form of Rab5, a small GTPase that regulates membrane traffic in the early endocytic pathway. This protein shares 42% sequence identity with Rabaptin-5, a previously...

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Detalhes bibliográficos
Main Authors: Gournier, H, Stenmark, H, Rybin, V, Lippé, R, Zerial, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170539/
https://ncbi.nlm.nih.gov/pubmed/9524116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.7.1930
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