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Cytokine Activation by Antibody Fragments Targeted to Cytokine-Receptor Signaling Complexes
Exogenous cytokine therapy can induce systemic toxicity, which might be prevented by activating endogenously produced cytokines in local cell niches. Here we developed antibody-based activators of cytokine signaling (AcCS), which recognize cytokines only when they are bound to their cell surface rec...
שמור ב:
| הוצא לאור ב: | J Biol Chem |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4697184/ https://ncbi.nlm.nih.gov/pubmed/26546677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.665943 |
| תגים: |
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