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Hypoxia Potentiates Palmitate-induced Pro-inflammatory Activation of Primary Human Macrophages
Pro-inflammatory cytokines secreted by adipose tissue macrophages (ATMs) contribute to chronic low-grade inflammation and obesity-induced insulin resistance. Recent studies have shown that adipose tissue hypoxia promotes an inflammatory phenotype in ATMs. However, our understanding of how hypoxia mo...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4697177/ https://ncbi.nlm.nih.gov/pubmed/26578520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.686709 |
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