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Hypoxia Potentiates Palmitate-induced Pro-inflammatory Activation of Primary Human Macrophages

Pro-inflammatory cytokines secreted by adipose tissue macrophages (ATMs) contribute to chronic low-grade inflammation and obesity-induced insulin resistance. Recent studies have shown that adipose tissue hypoxia promotes an inflammatory phenotype in ATMs. However, our understanding of how hypoxia mo...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Snodgrass, Ryan G., Boß, Marcel, Zezina, Ekaterina, Weigert, Andreas, Dehne, Nathalie, Fleming, Ingrid, Brüne, Bernhard, Namgaladze, Dmitry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697177/
https://ncbi.nlm.nih.gov/pubmed/26578520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.686709
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