Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases

Numerous membrane-bound proteins undergo regulated intramembrane proteolysis. Regulated intramembrane proteolysis is initiated by shedding, and the remaining stubs are further processed by intramembrane-cleaving proteases (I-CLiPs). Neuregulin 1 type III (NRG1 type III) is a major physiological subs...

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Publicat a:J Biol Chem
Autors principals: Fleck, Daniel, Voss, Matthias, Brankatschk, Ben, Giudici, Camilla, Hampel, Heike, Schwenk, Benjamin, Edbauer, Dieter, Fukumori, Akio, Steiner, Harald, Kremmer, Elisabeth, Haug-Kröper, Martina, Rossner, Moritz J., Fluhrer, Regina, Willem, Michael, Haass, Christian
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697167/
https://ncbi.nlm.nih.gov/pubmed/26574544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.697995
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