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The Nutrient-Responsive Transcription Factor TFE3, Promotes Autophagy, Lysosomal Biogenesis, and Clearance of Cellular Debris

The discovery of a gene network regulating lysosomal biogenesis and its transcriptional regulator TFEB revealed that cells monitor lysosomal function and respond to degradation requirements and environmental cues. Here, we report the identification of transcription factor E3 (TFE3) as another regula...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Martina, José A., Diab, Heba I., Lishu, Li, Jeong-A, Lim, Patange, Simona, Raben, Nina, Puertollano, Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696865/
https://ncbi.nlm.nih.gov/pubmed/24448649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004754
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