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The Nutrient-Responsive Transcription Factor TFE3, Promotes Autophagy, Lysosomal Biogenesis, and Clearance of Cellular Debris

The discovery of a gene network regulating lysosomal biogenesis and its transcriptional regulator TFEB revealed that cells monitor lysosomal function and respond to degradation requirements and environmental cues. Here, we report the identification of transcription factor E3 (TFE3) as another regula...

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Bibliografiske detaljer
Udgivet i:Sci Signal
Main Authors: Martina, José A., Diab, Heba I., Lishu, Li, Jeong-A, Lim, Patange, Simona, Raben, Nina, Puertollano, Rosa
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696865/
https://ncbi.nlm.nih.gov/pubmed/24448649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004754
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