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Impaired autophagy: The collateral damage of lysosomal storage disorders

Lysosomal storage disorders (LSDs), which number over fifty, are monogenically inherited and caused by mutations in genes encoding proteins that are involved in lysosomal function. Lack of the functional protein results in storage of a distinctive material within the lysosomes, which for years was t...

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Vydáno v:EBioMedicine
Hlavní autoři: Myerowitz, Rachel, Puertollano, Rosa, Raben, Nina
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753127/
https://ncbi.nlm.nih.gov/pubmed/33341443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103166
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