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Impaired autophagy: The collateral damage of lysosomal storage disorders

Lysosomal storage disorders (LSDs), which number over fifty, are monogenically inherited and caused by mutations in genes encoding proteins that are involved in lysosomal function. Lack of the functional protein results in storage of a distinctive material within the lysosomes, which for years was t...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Autores principales: Myerowitz, Rachel, Puertollano, Rosa, Raben, Nina
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753127/
https://ncbi.nlm.nih.gov/pubmed/33341443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103166
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