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Impaired autophagy: The collateral damage of lysosomal storage disorders

Lysosomal storage disorders (LSDs), which number over fifty, are monogenically inherited and caused by mutations in genes encoding proteins that are involved in lysosomal function. Lack of the functional protein results in storage of a distinctive material within the lysosomes, which for years was t...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Myerowitz, Rachel, Puertollano, Rosa, Raben, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7753127/
https://ncbi.nlm.nih.gov/pubmed/33341443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103166
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