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Calcineurin and Sorting-Related Receptor with A-Type Repeats Interact to Regulate the Renal Na(+)-K(+)-2Cl(−) Cotransporter
The furosemide-sensitive Na(+)-K(+)-2Cl(−)-cotransporter (NKCC2) is crucial for NaCl reabsorption in kidney thick ascending limb (TAL) and drives the urine concentrating mechanism. NKCC2 activity is modulated by N-terminal phosphorylation and dephosphorylation. Serine-threonine kinases that activate...
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| Publicado en: | J Am Soc Nephrol |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Nephrology
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4696563/ https://ncbi.nlm.nih.gov/pubmed/25967121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014070728 |
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