Short DNA sequences from the cytoplasm of mouse tumor cells induce immortalization of human lymphocytes in vitro.

Cytoplasts of mouse L929 and Ehrlich ascites tumor cells harbor DNA sequences that induce unlimited proliferation ("immortalization") of human lymphocytes after transfection in vitro. By equilibrium centrifugation of cytoplasmic lysates in a neutral CsCl gradient, the immortalizing activity was reco...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Abken, H, Hegger, R, Bützler, C, Willecke, K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46963/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8341663/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.14.6518
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