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Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in culture.

Human T-cell leukemia virus type 1 (HTLV-1) immortalizes human CD4+ T lymphocytes in culture. Previous studies show that in the context of a herpesvirus saimiri vector, the sequence of the X region at the 3' end of the HTLV-1 genome is also capable of immortalizing CD4+ lymphocytes in the absence of...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Grassmann, R, Berchtold, S, Radant, I, Alt, M, Fleckenstein, B, Sodroski, J G, Haseltine, W A, Ramstedt, U
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241270/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1351105/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.7.4570-4575.1992
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