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FXR Primes the Liver for Intestinal FGF15 Signaling by Transient Induction of β-Klotho
The bile acid (BA)-sensing nuclear receptor, farnesoid X receptor (FXR), regulates postprandial metabolic responses, including inhibition of BA synthesis, by inducing the intestinal hormone, fibroblast growth factor (FGF)15 (FGF19 in human). In this study, we tested a novel hypothesis that FXR not o...
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| Publicado no: | Mol Endocrinol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4695634/ https://ncbi.nlm.nih.gov/pubmed/26505219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1226 |
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