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Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA
We present the crystal structure of the junction-resolving enzyme GEN1 bound to DNA at 2.5 Å resolution. The structure of the GEN1 protein reveals it to have an elaborated FEN-XPG family fold that is modified for its role in four-way junction resolution. The functional unit in the crystal is a monom...
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| Опубликовано в: : | Cell Rep |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cell Press
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4695337/ https://ncbi.nlm.nih.gov/pubmed/26686639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.11.042 |
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