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Junction resolving enzymes use multivalency to keep the Holliday junction dynamic
Holliday junction (HJ) resolution by its resolving enzymes is essential for chromosome segregation and recombination-mediated DNA repair. HJs undergo two types of structural dynamics that determine the outcome of recombination: conformer exchange between two isoforms and branch migration. However, i...
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| Publicado no: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6377835/ https://ncbi.nlm.nih.gov/pubmed/30664685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0209-y |
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