LncRNA HOTAIR promotes human liver cancer stem cell malignant growth through downregulation of SETD2

Long non-coding RNA HOTAIR predicts negative tumor prognosis and exhibits oncogenic activity. Herein, we demonstrate HOTAIR promotes human liver cancer stem cell malignant growth through downregulation of SETD2. Mechanistically, HOTAIR reduces the recuritment of the CREB, P300, RNA polII onto the SE...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Li, Haiyan, An, Jiahui, Wu, Mengying, Zheng, Qidi, Gui, Xin, Li, Tianming, Pu, Hu, Lu, Dongdong
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695030/
https://ncbi.nlm.nih.gov/pubmed/26172293
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