LncRNA HOTAIR promotes human liver cancer stem cell malignant growth through downregulation of SETD2

Long non-coding RNA HOTAIR predicts negative tumor prognosis and exhibits oncogenic activity. Herein, we demonstrate HOTAIR promotes human liver cancer stem cell malignant growth through downregulation of SETD2. Mechanistically, HOTAIR reduces the recuritment of the CREB, P300, RNA polII onto the SE...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Haiyan, An, Jiahui, Wu, Mengying, Zheng, Qidi, Gui, Xin, Li, Tianming, Pu, Hu, Lu, Dongdong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695030/
https://ncbi.nlm.nih.gov/pubmed/26172293
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