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Long Noncoding RNA CUDR Regulates HULC and β-Catenin to Govern Human Liver Stem Cell Malignant Differentiation

Long noncoding RNA cancer upregulated drug resistant (CUDR) is overexpressed in many tumors and promotes tumorigenesis. Herein, we demonstrate CUDR could enhance the human embryonic stem cells (ESC) differentiation into hepatocyte-like cells by reducing trimethylation on histone H3 twenty-seventh ly...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Gui, Xin, Li, Haiyan, Li, Tianming, Pu, Hu, Lu, Dongdong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700108/
https://ncbi.nlm.nih.gov/pubmed/26347501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.166
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