Inflammatory cytokine IL6 cooperates with CUDR to aggravate hepatocyte-like stem cells malignant transformation through NF-κB signaling

Inflammatory cytokines and lncRNAs are closely associated with tumorigenesis. Herein, we reveal inflammatory cytokines IL6 cooperates with long noncoding RNA CUDR to trigger the malignant transformation of human embryonic stem cells-derived hepatocyte-like stem cells. Mechanistically, IL6 cooperates...

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Publicat a:Sci Rep
Autors principals: Zheng, Qidi, Lin, Zhuojia, Li, Xiaonan, Xin, Xiaoru, Wu, Mengying, An, Jiahui, Gui, Xin, Li, Tianming, Pu, Hu, Li, Haiyan, Lu, Dongdong
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104983/
https://ncbi.nlm.nih.gov/pubmed/27833137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36843
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