Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells

Post-transcriptional regulation is a powerful mediator of gene expression, and can rapidly alter the expression of numerous transcripts involved in tumorigenesis. We have previously shown that the mRNA-binding protein HuR (ELAVL1) is elevated in human pancreatic ductal adenocarcinoma (PDA) specimens...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Jimbo, Masaya, Blanco, Fernando F., Huang, Yu-Hung, Telonis, Aristeidis G., Screnci, Brad A., Cosma, Gabriela L., Alexeev, Vitali, Gonye, Gregory E., Yeo, Charles J., Sawicki, Janet A., Winter, Jordan M., Brody, Jonathan R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694992/
https://ncbi.nlm.nih.gov/pubmed/26314962
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