Analysis of SDHD promoter mutations in various types of melanoma

OBJECTIVES: Recently, recurrent mutations in regulatory DNA regions, such as promoter mutations in the TERT gene were identified in melanoma. Subsequently, Weinhold et al. reported SDHD promoter mutations occurring in 10% of melanomas and being associated with a lower overall survival rate. Our stud...

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Detalhes bibliográficos
Publicado no:Oncotarget
Principais autores: Scholz, Simone L., Horn, Susanne, Murali, Rajmohan, Möller, Inga, Sucker, Antje, Sondermann, Wiebke, Stiller, Mathias, Schilling, Bastian, Livingstone, Elisabeth, Zimmer, Lisa, Reis, Henning, Metz, Claudia H., Zeschnigk, Michael, Paschen, Annette, Steuhl, Klaus-Peter, Schadendorf, Dirk, Westekemper, Henrike, Griewank, Klaus G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694872/
https://ncbi.nlm.nih.gov/pubmed/26327518
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