Analysis of SDHD promoter mutations in various types of melanoma

OBJECTIVES: Recently, recurrent mutations in regulatory DNA regions, such as promoter mutations in the TERT gene were identified in melanoma. Subsequently, Weinhold et al. reported SDHD promoter mutations occurring in 10% of melanomas and being associated with a lower overall survival rate. Our stud...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Scholz, Simone L., Horn, Susanne, Murali, Rajmohan, Möller, Inga, Sucker, Antje, Sondermann, Wiebke, Stiller, Mathias, Schilling, Bastian, Livingstone, Elisabeth, Zimmer, Lisa, Reis, Henning, Metz, Claudia H., Zeschnigk, Michael, Paschen, Annette, Steuhl, Klaus-Peter, Schadendorf, Dirk, Westekemper, Henrike, Griewank, Klaus G.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694872/
https://ncbi.nlm.nih.gov/pubmed/26327518
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