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Coadministration of lapatinib increases exposure to docetaxel but not doxorubicin in the small intestine of mice
Combination therapy is increasingly being utilized for the treatment of metastatic breast cancer. However, coadministration of drugs, particularly agents that are substrates for or inhibitors of p-glycoprotein, can result in increased tissue toxicity. Unfortunately, determination of levels of chemot...
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| 發表在: | Anticancer Drugs |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4694043/ https://ncbi.nlm.nih.gov/pubmed/23928571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e3283645e1a |
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