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Coadministration of lapatinib increases exposure to docetaxel but not doxorubicin in the small intestine of mice
Combination therapy is increasingly being utilized for the treatment of metastatic breast cancer. However, coadministration of drugs, particularly agents that are substrates for or inhibitors of p-glycoprotein, can result in increased tissue toxicity. Unfortunately, determination of levels of chemot...
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| Vydáno v: | Anticancer Drugs |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4694043/ https://ncbi.nlm.nih.gov/pubmed/23928571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e3283645e1a |
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