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Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter
The c-kit oncogene is an important target in the treatment of gastrointestinal tumors. A potential approach to inhibition of the expression of this gene involves selective stabilization of G-quadruplex structures that may be induced to form in the c-kit promoter region. Here we report on the structu...
में बचाया:
| में प्रकाशित: | J Am Chem Soc |
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| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2007
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4693632/ https://ncbi.nlm.nih.gov/pubmed/17362008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja068739h |
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