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Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K(+) solution(†)

Intramolecular G-quadruplexes formed by human telomere sequences are attractive anticancer targets. Recently, four-repeat human telomere sequences have been shown to form two different intramolecular (3 + 1) G-quadruplexes in K(+) solution (Form 1 and Form 2). Here we report on the solution structur...

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Bibliographic Details
Main Authors: Phan, Anh Tuân, Kuryavyi, Vitaly, Luu, Kim Ngoc, Patel, Dinshaw J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095816/
https://ncbi.nlm.nih.gov/pubmed/17895279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm706
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