Human telomere, oncogenic promoter and 5′-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics

Guanine-rich DNA sequences can form G-quadruplexes stabilized by stacked G–G–G–G tetrads in monovalent cation-containing solution. The length and number of individual G-tracts and the length and sequence context of linker residues define the diverse topologies adopted by G-quadruplexes. The review h...

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Hlavní autoři: Patel, Dinshaw J., Phan, Anh Tuân, Kuryavyi, Vitaly
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
Survey and Summary
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190718/
https://ncbi.nlm.nih.gov/pubmed/17913750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm711
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