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Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter

It has been widely accepted that DNA can adopt other biologically relevant structures beside the Watson-Crick double helix. One recent important example is the guanine-quadruplex (G-quadruplex) structure formed by guanine tracts found in the MYC (or c-myc) promoter region, which regulates the transc...

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Detalhes bibliográficos
Publicado no:Nat Chem Biol
Main Authors: Phan, Anh Tuân, Kuryavyi, Vitaly, Gaw, Hai Yan, Patel, Dinshaw J
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690526/
https://ncbi.nlm.nih.gov/pubmed/16408022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio723
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