Type 5 adenylyl cyclase disruption leads to enhanced exercise performance

The most important physiological mechanism mediating enhanced exercise performance is increased sympathetic, beta adrenergic receptor (β‐AR), and adenylyl cyclase (AC) activity. This is the first report of decreased AC activity mediating increased exercise performance. We demonstrated that AC5 disru...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Vatner, Dorothy E., Yan, Lin, Lai, Lo, Yuan, Chujun, Mouchiroud, Laurent, Pachon, Ronald E., Zhang, Jie, Dillinger, Jean‐Guillaume, Houtkooper, Riekelt H., Auwerx, Johan, Vatner, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693460/
https://ncbi.nlm.nih.gov/pubmed/26424149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12401
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