Type 5 adenylyl cyclase disruption leads to enhanced exercise performance

The most important physiological mechanism mediating enhanced exercise performance is increased sympathetic, beta adrenergic receptor (β‐AR), and adenylyl cyclase (AC) activity. This is the first report of decreased AC activity mediating increased exercise performance. We demonstrated that AC5 disru...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Vatner, Dorothy E., Yan, Lin, Lai, Lo, Yuan, Chujun, Mouchiroud, Laurent, Pachon, Ronald E., Zhang, Jie, Dillinger, Jean‐Guillaume, Houtkooper, Riekelt H., Auwerx, Johan, Vatner, Stephen F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693460/
https://ncbi.nlm.nih.gov/pubmed/26424149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12401
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