IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

Aging is associated with marked deficiency in circulating IGF‐1, which has been shown to contribute to age‐related cognitive decline. Impairment of moment‐to‐moment adjustment of cerebral blood flow (CBF) via neurovascular coupling is thought to play a critical role in the genesis of age‐related cog...

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Publicado en:Aging Cell
Autores principales: Toth, Peter, Tarantini, Stefano, Ashpole, Nicole M., Tucsek, Zsuzsanna, Milne, Ginger L., Valcarcel‐Ares, Noa M., Menyhart, Akos, Farkas, Eszter, Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2015
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693458/
https://ncbi.nlm.nih.gov/pubmed/26172407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12372
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