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Gating the glutamate gate of CLC-2 chloride channel by pore occupancy

CLC-2 channels are dimeric double-barreled chloride channels that open in response to hyperpolarization. Hyperpolarization activates protopore gates that independently regulate the permeability of the pore in each subunit and the common gate that affects the permeability through both pores. CLC-2 ch...

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Veröffentlicht in:J Gen Physiol
Hauptverfasser: De Jesús-Pérez, José J., Castro-Chong, Alejandra, Shieh, Ru-Chi, Hernández-Carballo, Carmen Y., De Santiago-Castillo, José A., Arreola, Jorge
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692487/
https://ncbi.nlm.nih.gov/pubmed/26666914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511424
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