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Gating the glutamate gate of CLC-2 chloride channel by pore occupancy

CLC-2 channels are dimeric double-barreled chloride channels that open in response to hyperpolarization. Hyperpolarization activates protopore gates that independently regulate the permeability of the pore in each subunit and the common gate that affects the permeability through both pores. CLC-2 ch...

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Détails bibliographiques
Publié dans:J Gen Physiol
Auteurs principaux: De Jesús-Pérez, José J., Castro-Chong, Alejandra, Shieh, Ru-Chi, Hernández-Carballo, Carmen Y., De Santiago-Castillo, José A., Arreola, Jorge
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692487/
https://ncbi.nlm.nih.gov/pubmed/26666914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511424
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