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Permeant anions contribute to voltage dependence of ClC-2 chloride channel by interacting with the protopore gate
It has been shown that the voltage (V(m)) dependence of ClC Cl(−) channels is conferred by interaction of the protopore gate with H(+) ions. However, in this paper we present evidence which indicates that permeant Cl(−) ions contribute to V(m)-dependent gating of the broadly distributed ClC-2 Cl(−)...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916987/ https://ncbi.nlm.nih.gov/pubmed/20498235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.189175 |
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