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CD40-TRAF Signaling Upregulates CX3CL1 and TNF-α in Human Aortic Endothelial Cells but Not in Retinal Endothelial Cells

CD40, CX3CL1 and TNF-α promote atheroma and neointima formation. CD40 and TNF-α are also central to the development of diabetic retinopathy while CX3CL1 may play a role in the pathogenesis of this retinopathy. The purpose of this study was to examine whether CD40 ligation increases CX3CL1 and TNF-α...

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Vydáno v:PLoS One
Hlavní autoři: Greene, Jennifer A., Portillo, Jose-Andres C., Lopez Corcino, Yalitza, Subauste, Carlos S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692437/
https://ncbi.nlm.nih.gov/pubmed/26710229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144133
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